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NMDAR2C Antibody

CAT: 0800-R32230Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32230Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NMDAR2C, known as GRIN2C, is mapped to 17q25.1. Glutamate [NMDA] receptor subunit epsilon-3 is a protein that in humans is encoded by the GRIN2C gene. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL
UniProt
Q14957
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Amino acids 43-242 of human NMDAR2C were used as the immunogen for the NMDAR2C antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the NMDAR2C antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This NMDAR2C antibody is available for research use only.
Storage Conditions
After reconstitution, the NMDAR2C antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the NMDAR2C antibody should be determined by the researcher.
Image Legend
Western blot testing of rat brain lysate with NMDAR2C antibody. Expected/observed molecular weight ~134 kDa.
Product Datasheet
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