NMDAR2B Antibody

CAT: 0800-R30240Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R30240Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The N-methyl-D-aspartate receptor 2B is also called GRIN2B. The sequence of the predicted 1,484-amino acid human protein is 98% and 96% identical to the sequences of the rat and mouse proteins, respectively. The gene is located on mouse chromosome 6 between Rho and Ly49 centromerically and Glb telomerically. Overexpression of NMDAR2B in the forebrains of transgenic mice leads to enhanced activation of NMDA receptors, facilitating synaptic potentiation in response to stimulation at 10-100 Hz.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q13224
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids 1307-1320 (FVDLQKEEAALAPR) were used as the immunogen for this NMDAR2B antibody (100% homologous in human, mouse and rat) .
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the NMDAR2B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This NMDAR2B antibody is available for research use only.
Storage Conditions
After reconstitution, the NMDAR2B antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the NMDAR2B antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of NMDAR2B antibody and Lane 1: rat brain; 2: mouse brain; 3: human U87 cell lysate. Predicted molecular weight ~166kDa.

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