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PLD1 Antibody

CAT: 0800-R32213Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32213Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
By somatic cell hybrid analysis, PLD1 is mapped to 3q26.31. This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. And PLD1 disrupted association of gamma-secretase protein components, independent of PLD1catalytic activity. What's more, PLD1 regulates intracellular trafficking of beta-amyloid, distinct from its effect on gamma-secretase activity.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL
UniProt
Q13393
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Amino acids 1-330 of human PLD1 were used as the immunogen for the PLD1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the PLD1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This PLD1 antibody is available for research use only.
Storage Conditions
After reconstitution, the PLD1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the PLD1 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) mouse heart, 2) human 22RV1 and 3) human HeLa cell lysate with PLD1 antibody. Expected/observed molecular weight: ~124 kDa.
Product Datasheet
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