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TRAP1 Antibody / HSP75

CAT: 0800-R32204Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32204Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Heat shock protein 75 kDa, mitochondrial is a protein that in humans is encoded by the TRAP1 gene. It is mapped to 16p13.3. This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. And this protein may function in regulating cellular stress responses. In addition, it was found that TRAP1 interacted with the N-terminal half of TNFR1. Also, TRAP1 interacted with the C-terminal ends of the proteins encoded by both multiple exostoses-causing genes, EXT1 and EXT2, but not with EXTL1 or EXTL3.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
Q12931
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Amino acids 571-704 of human TRAP1 were used as the immunogen for the TRAP1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the TRAP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TRAP1 antibody is available for research use only.
Storage Conditions
After reconstitution, the TRAP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the TRAP1 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Western blot testing of 1) rat heart, 2) rat kidney, 3) rat brain, 4) human SMMC, 5) human PANC and 6) human A549 lysate with TRAP1 antibody. Expected molecular weight: 75-80 kDa.