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Lysozyme Antibody / LYZ

CAT: 0800-R32157Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32157Size:100 µg
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Description
In humans, the lysozyme enzyme is encoded by the LYZ gene. This gene encodes human lysozyme c, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta [1-4] glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine) . Lysozyme is one of the antimicrobial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. The protein has antibacterial activity against a number of bacterial species. Missense mutations in this gene have been identified in heritable renal amyloidosis.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL, Immunofluorescence: 5-7 µg/mL
UniProt
P61626
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids NIADAVACAKRVVRDPQGIRAWVAWRNRCQNRDVRQ of human LYZ were used as the immunogen for the Lysozyme antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IF
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the Lysozyme antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Lysozyme antibody is available for research use only.
Storage Conditions
After reconstitution, the Lysozyme antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Lysozyme antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Immunofluorescent staining of FFPE human colon with Lysozyme antibody (red) and DAPI (blue) . HIER: Boil the paraffin sections in pH 6, 10mM citrate buffer for 20 minutes and allow to cool prior to staining.

UniProtKB · P61626

Lysozyme C

LYSC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P61626
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LYZ
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.2.1.17
Processing
Precursor
Secondary accessions
P00695, Q13170, Q9UCF8
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

AmyloidSecreted

Disease

AmyloidosisDisease variant

Molecular function

AntimicrobialBacteriolytic enzymeGlycosidaseHydrolase

PTM

Disulfide bond

Domain

Signal
Product Datasheet
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