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WNT3 Antibody

CAT: 0800-R32152Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32152Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL
UniProt
P56703
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids AMNKHNNEAGRTTILDHMHLKCK of human WNT3A were used as the immunogen for the WNT3 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the WNT3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This WNT3 antibody is available for research use only.
Storage Conditions
After reconstitution, the WNT3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the WNT3 antibody should be determined by the researcher.
Image Legend
Western blot testing of human 1) placenta and 2) HepG2 lysate with WNT3 antibody. Expected/observed size 35~44 kDa depending on glycosylation level.

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