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RIP140 Antibody / NRIP1

CAT: 0800-R32110Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32110Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nuclear receptor-interacting protein 1 (NRIP1), also known as receptor-interacting protein 140 (RIP140), is a protein that in humans is encoded by the NRIP1 gene. It is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein is a key regulator which modulates transcriptional activity of a variety of transcription factors, including the estrogen receptor. RIP140 has an important role in regulating lipid and glucose metabolism, and regulates gene expression in metabolic tissues including heart, skeletal muscle, and liver. A major role for RIP140 in adipose tissue is to block the expression of genes involved in energy dissipation and mitochondrial uncoupling, including uncoupling protein 1 and carnitine palmitoyltransferase 1b.
CAS Number
9007-83-4
UniProt
P48552
Host
Rabbit
Immunogen
Amino acids EAHLQQYSREHALKTQNANQAASERLAAMARLQE of human RIP140/NRIP1 were used as the immunogen for the RIP140 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Format
Antigen affinity purified
Buffer
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Reconstitution
After reconstitution, the RIP140 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This RIP140 antibody is available for research use only.

UniProtKB · P48552

Nuclear receptor-interacting protein 1

NRIP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P48552
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NRIP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q8IWE8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

Activator

Biological process

Biological rhythmsTranscriptionTranscription regulation

Cellular component

Nucleus

Domain

Repeat
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TA305768RIP140 (NRIP1) Goat Polyclonal Antibody
TA379315RIP140 (NRIP1) Rabbit Polyclonal Antibody
RP1095-Cy3Anti-RIP140/NRIP1 Antibody Picoband® (Cy3 Conjugate)
RP1095-Dylight550Anti-RIP140/NRIP1 Antibody Picoband® (Dylight550 Conjugate)
RP1095-APCAnti-RIP140/NRIP1 Antibody Picoband® (APC Conjugate)
RP1095-PEAnti-RIP140/NRIP1 Antibody Picoband® (PE Conjugate)
RP1095-Dylight488Anti-RIP140/NRIP1 Antibody Picoband® (Dylight488 Conjugate)
RP1095-FITCAnti-RIP140/NRIP1 Antibody Picoband® (FITC Conjugate)
RP1095-HRPAnti-RIP140/NRIP1 Antibody Picoband® (HRP Conjugate)
RP1095-BiotinAnti-RIP140/NRIP1 Antibody Picoband® (Biotine Conjugate)

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