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PAX6 Antibody

CAT: 0800-R32035Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R32035Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Paired box protein Pax-6, also known as aniridia type II protein (AN2) or oculorhombin, is a protein that in humans is encoded by the PAX6 gene. This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. In addition, this gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
P26367
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids EDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTH of human PAX6 were used as the immunogen for the PAX6 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the PAX6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This PAX6 antibody is available for research use only.
Storage Conditions
After reconstitution, the PAX6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the PAX6 antibody should be determined by the researcher.
Location
Nuclear, cytoplasmic
Image Legend
Western blot testing of 1) rat brain, 2) mouse brain, 3) human U87 and 4) human HeLa lysate with PAX6 antibody. Expected/observed molecular weight ~48 kDa.

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