BMP6 Antibody

• Description:

  Bone morphogenetic protein 6 is a protein that in humans is encoded by the BMP6 gene. The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

• Specifications:

  Western blot: 0.1-0.5 µg/mL, FACS: 1-3ug/10^6 cells, ELISA: 0.1-0.5 µg/mL (human protein tested) ; request BSA-free format for coating

• UniProt:

  P22004

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Amino acids QSRNRSTQSQDVARVSSASDYNSSELKTACRKHELYV of human BMP6 were used as the immunogen for the BMP6 antibody.

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  WB, FACS, ELISA (protein)

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

• Reconstitution:

  After reconstitution, the BMP6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations:

  This BMP6 antibody is available for research use only.

• Storage Conditions:

  After reconstitution, the BMP6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation:

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes:

  Optimal dilution of the BMP6 antibody should be determined by the researcher.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of human HeLa cell lysate with BMP6 antibody. Expected molecular weight: ~57 kDa (precursor), ~46 kDa (cleaved precursor), 18-23 kDa (mature) .