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PTPN2 Antibody

CAT: 0800-R31988Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31988Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TCPTP is also called as PTPN2. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
P17706
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Amino acids 1-330 of human PTPN2 were used as the immunogen for the PTPN2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the PTPN2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This PTPN2 antibody is available for research use only.
Storage Conditions
After reconstitution, the PTPN2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the PTPN2 antibody should be determined by the researcher.
Location
Nuclear
Image Legend
Western blot testing of human 1) HeLa and 2) Jurkat lysate with PTPN2 antibody. Predicted/observed molecular weight ~48 kDa.

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