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Synaptophysin Antibody

CAT: 0800-R31914Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31914Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SYP (Synaptophysin) is located on the short arm of X chromosome (Xp11.23-p11.22) . The protein is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38kDa. It is present inneuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a marker for neuroendocrine tumors, and its ubiquity at the synapse has led to the use of synaptophysin immunostaining for quantification of synapses. Also, the protein binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR) .
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL
UniProt
P08247
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids MLLLADMDVVNQLVAGGQFRVVKEPL of human Synaptophysin were used as the immunogen for the Synaptophysin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the Synaptophysin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Synaptophysin antibody is available for research use only.
Storage Conditions
After reconstitution, the Synaptophysin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Synaptophysin antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat brain and 2) mouse brain lysate with Synaptophysin antibody. Predicted/observed molecular weight: 34~38 kDa.

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