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APG7 Antibody

CAT: 0800-R31845Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31845Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Autophagy-related protein 7 is a protein that in humans is encoded by the ATG7 gene. It is mapped to 3p25.3. This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein also shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes. ATG7 is essential for the Apg12 conjugation system that mediates membrane fusion in autophagy. It is found that when nutrients are limited, ATG7 can regulate p53-dependent cell cycle and cell death pathways.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL
UniProt
O95352
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids HSFLEDLTGLTLLHQETQAAEIWDMSDDETI of human APG7 were used as the immunogen for the APG7 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the APG7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This APG7 antibody is available for research use only.
Storage Conditions
After reconstitution, the APG7 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the APG7 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat brain, 2) mouse brain and 3) human 293 lysate with APG7 antibody. Predicted molecular weight: 70-80 kDa.

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