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SOCS2 Antibody

CAT: 0800-R31798Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31798Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Suppressor of cytokine signaling 2 is a protein that in humans is encoded by the SOCS2 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signalling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon-gamma (IFN-gamma) . The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor 1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. By cytogenetic and radiation hybrid mapping, Yandava et al. (1999) mapped the SOCS2 gene to chromosome 12q21.3-q23.
CAS Number
9007-83-4
Specifications
Western blot: 0.1-0.5 µg/mL
UniProt
O14508
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Amino acids 96-198 of human SOCS2 were used as the immunogen for the SOCS2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the SOCS2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This SOCS2 antibody is available for research use only.
Storage Conditions
After reconstitution, the SOCS2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the SOCS2 antibody should be determined by the researcher.
Image Legend
Western blot testing of 1) rat PC12, human 2) SW620, 3) HeLa and 4) MCF7 lysate with SOCS2 antibody. Expected/observed molecular weight: 22 kDa.

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