Products for Research Use Only

PSA Antibody / Prostate Specific Antigen

CAT: 0800-R31672Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31672Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. It is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. This gene is mapped to 19q13.33. PSA is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. It is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving the cervical mucous cap, allowing the entry of sperm. PSA level is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P07288
Host
Rabbit
Reactivity
Human
Immunogen
Human partial recombinant protein (AA 25-261) was used as the immunogen for this PSA antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the PSA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This PSA antibody is available for research use only.
Storage Conditions
After reconstitution, the PSA antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the PSA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
IHC staining of FFPE human prostate cancer tissue with c-Kit antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.