KLF4 Antibody

• Description :

  Kruppel-like factor 4 (KLF4) is a transcription factor involved in both proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas and has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. KLF4 is also involved in reprogramming differentiated cells into pluripotent stem cells. KLF4 can act as a transcriptional activator or repressor, but the underlying mechanisms are poorly understood.

• Specifications :

  Western blot: 1:1000

• UniProt :

  O43474

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  A portion of amino acids 20-53 from the human protein was used as the immunogen for this KLF4 antibody.

• Clonality :

  Polyclonal

• Isotype :

  Ig

• Applications :

  WB, ELISA

• Purity :

  Purified

• Format :

  Purified

• Buffer :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution :

  Aliquot the KLF4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations :

  This KLF4 antibody is available for research use only.

• Storage Conditions :

  Aliquot the KLF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes :

  Titration of the KLF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number :

  9007-83-4

• Image Legend :

  KLF4 antibody western blot analysis in (1) HeLa, (2) MCF-7 and (3) SW480 lysate. Predicted molecular weight: 50-60 kDa + possible ~75 kDa (phosphorylated form) .