KLF4 Antibody

• Description:

  Kruppel-like factor 4 (KLF4) is a transcription factor involved in both proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas and has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. KLF4 is also involved in reprogramming differentiated cells into pluripotent stem cells. KLF4 can act as a transcriptional activator or repressor, but the underlying mechanisms are poorly understood.

• Specifications:

  Western blot: 1:1000

• UniProt:

  O43474

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 20-53 from the human protein was used as the immunogen for this KLF4 antibody.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Purified

• Format:

  Purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the KLF4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This KLF4 antibody is available for research use only.

• Storage Conditions:

  Aliquot the KLF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the KLF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  KLF4 antibody western blot analysis in (1) HeLa, (2) MCF-7 and (3) SW480 lysate. Predicted molecular weight: 50-60 kDa + possible ~75 kDa (phosphorylated form) .