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FGFR4 Antibody

CAT: 0800-R31606Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31606Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FGFR4 (Fibroblast growth factor receptor 4), also known as CD334, is a protein that in humans is encoded by the FGFR4 gene. It is mapped to 5q35.2. The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. It is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
Host
Rabbit
Reactivity
Human
Immunogen
Human partial recombinant protein (AA 22-206) was used as the immunogen for this FGFR4 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the FGFR4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This FGFR4 antibody is available for research use only.
Storage Conditions
After reconstitution, the FGFR4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the FGFR4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of FGFR4 antibody and Lane 1: HeLa; 2: PANC; 3: SGC; 4: COLO320; 5: SW620; Observed molecular weight: 88~125 kDa depending on phosphorylation and glycosylation level.

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