SynCAM Antibody

• Description :

  Cell adhesion molecule 1 is a protein that, in humans, is encoded by the CADM1 gene. This gene is also known as IGSF4, SYNCAM or TSLC1, and it is mapped to 11q23.3. It functions as a homophilic cell adhesion molecule at the synapse. Expression of the isolated cytoplasmic tail of SynCAM in neurons inhibited synapse assembly. Conversely, expression of full-length protein in nonneuronal cells induced synapse formation by cocultured hippocampal neurons with normal release properties.

• Specifications :

  Western blot: 0.5-1 µg/mL

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Human partial recombinant protein (AA 45-340) was used as the immunogen for this SynCAM antibody.

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  WB

• Purity :

  Antigen affinity

• Format :

  Antigen affinity purified

• Buffer :

  Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide

• Reconstitution :

  After reconstitution, the SynCAM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations :

  This SynCAM antibody is available for research use only.

• Storage Conditions :

  After reconstitution, the SynCAM antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation :

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes :

  The stated application concentrations are suggested starting amounts. Titration of the SynCAM antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number :

  9007-83-4

• Image Legend :

  Western blot testing of SynCAM antibody and Lane 1: rat brain; 2: human HeLa; 3: (h) A549; 4: (h) Jurkat. Predicted molecular weight: ~48/37 kDa (isoforms 1/2) with N-linked and O-linked glycosylation each possibly adding ~25 kDa to the observed size.