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IL-6 Antibody

CAT: 0800-R31438Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31438Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Interleukin-6 is a protein that in humans is encoded by the IL6 gene. It is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. IL-6 is one of the most important mediators of fever and of the acute phase response. It is also essential for hybridoma growth and is found in many supplemental cloning media such as briclone. Bowcock et al. (1988) assigned the IL6 gene to chromosome 7p21. By in situ hybridization and Southern blot analysis of mouse-human hybrid cell lines, Sutherland et al. (1988) mapped the gene to chromosome 7p15.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P20607
Host
Rabbit
Reactivity
Rat
Immunogen
Rat partial recombinant protein (AA 25-211) was used as the immunogen for this IL-6 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
Reconstitution
After reconstitution, the IL-6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This IL-6 antibody is available for research use only.
Storage Conditions
After reconstitution, the IL-6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting points. Titration of the IL-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of IL-6 antibody (0.5ug/ml) and recombinant rat protein (0.5ng)

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