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CADM1 Antibody

CAT: 0800-R31418Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31418Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cell adhesion molecule 1 is a protein that, in humans, is encoded by the CADM1 gene. This gene is also known as IGSF4, SYNCAM or TSLC1, and it is mapped to 11q23.3. It functions as a homophilic cell adhesion molecule at the synapse. Expression of the isolated cytoplasmic tail of CADM1 in neurons inhibited synapse assembly. Conversely, expression of full-length protein in non-neuronal cells induced synapse formation by cocultured hippocampal neurons with normal release properties. It has been shown to interact with EPB41L3.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q9BY67
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the N-terminus of human SynCAM/CADM1 (VIQLLNPNRQTIYFRDFRPL) was used as the immunogen for this CADM1 antibody (100% homologous in human, mouse and rat) .
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the CADM1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CADM1 antibody is available for research use only.
Storage Conditions
After reconstitution, the CADM1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the CADM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of CADM1 antibody and Lane 1: A549; 2: Jurkat; 3: Raji; 4: HeLa lysate. Predicted molecular weight: ~48/37kDa (isoforms 1/2) with N-linked and O-linked glycosylation each possibly adding ~25kDa to the observed size.

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MBS8587758-01CADM1 Antibody

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