Products for Research Use Only
RegisterLogin

Leupaxin Antibody

CAT: 0800-R31317Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R31317Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Leupaxin is a protein that in humans is encoded by the LPXN gene. This gene is mapped to 11q12.1. The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, Leupaxin may also function in, and be regulated by, tyrosine kinase activity.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
O60711
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the N-terminus of human Leupaxin (KKHLPDKQDHKASLD) was used as the immunogen for this Leupaxin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the Leupaxin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Leupaxin antibody is available for research use only.
Storage Conditions
After reconstitution, the Leupaxin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the Leupaxin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of Leupaxin antibody and Lane 1: rat thymus; 2: human Jurkat cell lysate. Expected/observed size ~43KD

UniProtKB · O60711

Leupaxin

LPXN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O60711
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LPXN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R8B4, B4DV71, Q53FW6, Q6FI07
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Molecular function

Activator

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesionTranscriptionTranscription regulation

Cellular component

Cell junctionCell membraneCell projectionCytoplasmMembraneNucleus

Domain

LIM domainRepeat

Ligand

Metal-bindingZinc

Related Products

CatalogName
FY12903LPXN Antibody / Leupaxin
RQ4624NONO Antibody / p54nrb Antibody
F53952-0.2MLAntibody
F53952-0.05MLAntibody
F53954-0.2MLAntibody
F53954-0.05MLAntibody
V8674SAF-100UGInhibin alpha Antibody / INHA antibody
V8674-100UGInhibin alpha Antibody / INHA antibody
V8674-20UGInhibin alpha Antibody / INHA antibody
R20179SAF-250UGLambda Light Chain Antibody / Lambda Antibody

Alternative Products

CatalogName
ASA-B1166Leupaxin Antibody
abx301939-01Leupaxin (LPXN) Antibody
MBS176960-01Anti-Leupaxin antibody
bs-13653RLeupaxin Polyclonal Antibody
GTR18113382-01Leupaxin Rabbit Polyclonal Antibody
NBP3-03286-100ulRabbit Polyclonal Leupaxin Antibody
MBS2032229-01Leupaxin (LPXN) Polyclonal Antibody
H00009404-B01PMouse Polyclonal Leupaxin Antibody
abx304375-01Leupaxin (LPXN) Antibody (HRP)
abx304377-01Leupaxin (LPXN) Antibody (Biotin)

Popular Products