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Tuberin Antibody

CAT: 0800-R31296Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31296Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tuberous sclerosis 2 protein, also known as TSC2 or Tuberin, is human protein. The chromosomal location of this gene is 16p13.3. Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. This gene involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. It stimulates weakly the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5 in vitro.
CAS Number
9007-83-4
UniProt
P49815
Host
Rabbit
Immunogen
An amino acid sequence from the C-terminus of human Tuberin (QFTYCWHDDIMQAVFH) was used as the immunogen for this Tuberin antibody (100% homologous in human, mouse and rat).
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Format
Antigen affinity purified
Buffer
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Reconstitution
After reconstitution, the Tuberin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Tuberin antibody is available for research use only.

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