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Cd134 Antibody / Ox40

CAT: 0800-R31252Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31252Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tumor necrosis factor receptor superfamily, member4, also known as ACT35 or CD134 is a cell surface glycoprotein that was discovered through the production of a monoclonal antibody raised against the HUT-102 cell line. It belongs to the tumor necrosis factor receptor superfamily. OX40 was mapped to 1p36 by fluorescence in situ hybridization. CD134 is the primary receptor for feline immunodeficiency virus. OX40 expression can promote viral binding and renders cells permissive for viral entry, productive infection, and syncytium formation. Stimulating the receptor can improve the response to a powerful virus vector and may be useful in vaccine development.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P47741
Host
Rabbit
Reactivity
Mouse
Immunogen
An amino acid sequence from the N-terminus of mouse CD134/OX40 (ARRLNCVKHTYPSGHKCCRECQ) was used as the immunogen for this Cd134 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the CD134 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Cd134 antibody is available for research use only.
Storage Conditions
After reconstitution, the Cd134 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the Cd134 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic, membranous
Image Legend
Western blot testing of Cd134 antibody and mouse samples 1: brain; 2: spleen; 3: liver tissue lysate. Expected molecular weight: 29-50 kDa depending on glcyosylation level.

UniProtKB · P47741

Tumor necrosis factor receptor superfamily member 4

TNR4_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P47741
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Tnfrsf4
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

PTM

Disulfide bondGlycoprotein

Cellular component

Membrane

Molecular function

Receptor

Technical term

Reference proteome

Domain

RepeatSignalTransmembraneTransmembrane helix

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