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NFKB1 Antibody

CAT: 0800-R31224Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31224Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nuclear factor NF-kappa-B p105/p50, also called EBP-1 is a protein that in humans is encoded by the NFKB1 gene. By fluorescence in situ hybridization, the gene was assigned to human chromosome 4q24. NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P19838
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the N-terminus of human NFkB p105/p50 (KELIRQAALQQTKEMD) was used as the immunogen for this NFKB1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the NFKB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This NFKB1 antibody is available for research use only.
Storage Conditions
After reconstitution, the NFKB1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the NFKB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of NFKB1 antibody and 1. HeLa and 2. Jurkat cell lysate. Expected molecular weight: 50 kDa / 105 kDa.
Product Datasheet
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