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TRPV2 Antibody (VRL1)

CAT: 0800-R31083Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R31083Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transient Receptor Potential Cation Channel Subfamily V Member 2, also known as VRL1, is a protein that, in humans, is encoded by the TRPV2 gene. The International Radiation Hybrid Mapping Consortium mapped the TRPV2 gene to chromosome 17. This gene encodes an ion channel that is activated by high temperatures above 52oC. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is though that in other tissues the channel may be activated by stimuli other than heat.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL, Immunohistochemistry (Frozen) : 0.5-1 µg/mL
UniProt
Q9Y5S1
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids 42-624 (QFQGEDRKFAPQIRVNLNYRK-human) were used as the immunogen for this TRPV2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P, IHC-F
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the TRPV2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TRPV2 antibody is available for research use only.
Storage Conditions
After reconstitution, the TRPV2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the TRPV2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of TRPV2 antibody and HeLa cell lysate. Expected molecular weight: 85-95 kDa depending on glycosylation level.

UniProtKB · Q9Y5S1

Transient receptor potential cation channel subfamily V member 2

TRPV2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y5S1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TRPV2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
TrpV2
EC number
—
Processing
—
Secondary accessions
A6NML2, A8K0Z0, Q9Y670
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Domain

ANK repeatRepeatTransmembraneTransmembrane helix

Ligand

Calcium

Molecular function

Calcium channelIon channel

Biological process

Calcium transportIon transportTransport

Cellular component

Cell membraneCytoplasmMembrane

PTM

GlycoproteinPhosphoprotein
Product Datasheet
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