TXNRD2 Antibody

• Description:

  Thioredoxin reductase 2 is also known as TRXR2, TR3, SELZ, or TR-BETA. Thioredoxin reductases, are selenocysteine (sec) -containing flavoenzymes that maintain thioredoxins, small proteins that catalyze redox reactions, in the reduced state using the reducing power of NADPH. By STS analysis and genomic sequence analysis, respectively, Miranda-Vizuete et al. (1999) and Sun et al. (1999) mapped the TXNRD2 gene to chromosome 22q11.2. Miranda-Vizuete et al. (1999) mapped the mouse gene to chromosome 16. Gasdaska et al. (1999) showed that TXNRD2 was a thioredoxin reductase that could directly reduce proteins such as insulin.

• Specifications:

  Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL

• UniProt:

  Q9NNW7

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  An amino acid sequence from the C-terminus of human TXNRD2 (RHGQEHVEVYHAHYKPL) was used as the immunogen for this TXNRD2 antibody.

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  WB, IHC-P

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal

• Reconstitution:

  After reconstitution, the TXNRD2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

• Limitations:

  This TXNRD2 antibody is available for research use only.

• Storage Conditions:

  After reconstitution, the TXNRD2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

• Formulation:

  0.5 mg/mL if reconstituted with 0.2ml sterile DI water

• Applications Notes:

  The stated application concentrations are suggested starting amounts. Titration of the TXNRD2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of TXNRD2 antibody and rat samples 1: kidney; 2: ovary; 3: liver; 4: human SMMC-7721 cell lysate