DDR2 Antibody

CAT: 0800-R30979Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R30979Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Discoidin domain receptor family, member 2, also known as NTRKR3 or TKT, is a human gene. DDR2 protein was detected in most mouse tissues examined. Highest levels of phosphorylated protein were detected in lung, ovary, and skin, which did not correlate with DDR2 protein levels. The gene is mapped 1q23.3. DDRs play a key role in the communication of cells with their microenvironment. Using in situ hybridization with 1-week-old mice, Labrador et al. (2001) found that DDR2 was expressed along chondrocyte columns in the proliferative region of the growth plate. mRNA was also present, although dispersed, at areas of calcified cartilage in the cartilage-bone junction, as well as in the trabecular bone surface. Bargal et al. (2009) also identified a splice site mutation in the gene, which resulted in the skipping of exon 17, in one of the Jewish families with SMED-SL originally reported by Borochowitz et al. (1993) .
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
Q16832
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human DDR2 (RDTKNRPSFQEIHLLLLQQGDE) was used as the immunogen for this DDR2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the DDR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This DDR2 antibody is available for research use only.
Storage Conditions
After reconstitution, the DDR2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the DDR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of DDR2 antibody and Lane 1: recombinant human protein 10ng; 2: 5ng; 3: 2.5ng

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