Products for Research Use Only
RegisterLogin

CD1d Antibody

CAT: 0800-R30948Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0800-R30948Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CD1d is the sole group-2 member of the CD1 family of major histocompatibility (MHC) -like glycoproteins expressed on the surface of various human antigen-presenting cells. They are related to the class I MHC molecules, and are involved in the presentation of lipid antigens to T cells. CD1d presented lipid antigens activate a special class of T cells, known as Natural Killer T (NKT) cells. When activated, NKT cells rapidly produce Th1 and Th2 cytokines, typically represented by interferon-gamma and IL-4 production. Jayawardena-Wolf et al. described 2 different pathways of CD1d trafficking to endosomal compartments in mouse cells. A tyrosine-based motif governs recycling between the plasma membrane and the endosome, while CD1d associates, like major histocompatibility complex class II antigens, with the invariant chain, or II, in the endoplasmic reticulum. Both pathways enhance antigen presentation to CD1d-restricted natural killer T cells.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
P15813
Host
Rabbit
Reactivity
Human
Immunogen
Amino acids 76-92 (FSDQQWETLQHIFRVYR-human) were used as the immunogen for this CD1d antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the CD1d antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This CD1d antibody is available for research use only.
Storage Conditions
After reconstitution, the CD1d antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the CD1d antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of CD1d antibody and Lane 1: COLO320; 2: HeLa; 3: HT1080; 4: Jurkat cell lysate

Related Products

CatalogName
RQ7965Cd19 Antibody
V3203-100UGCD15 Antibody
R35348-100UGCD13 Antibody
F46544-0.08MLCD1b Antibody
F49569-0.4MLCD14 Antibody
V2389SAF-100UGCD19 Antibody
V2645-100UGCD18 Antibody
V8858-100UGCD16 Antibody
RQ4156CD19 Antibody
V2026IHC-7MLCD1a Antibody

Alternative Products

CatalogName
70R-12862CD1D antibody
144311CD1D (R3G1, CD1d)
033471CD1D, ID (CD1D, Antigen-presenting glycoprotein CD1d, R3G1, CD1d)

Popular Products