Caveolin-2 Antibody

CAT: 0800-R30617Size: 100 µgDry Ice: NoHazardous: No
CAT#:0800-R30617Size:100 µg
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Description
Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes. CAV2 and CAV1 are similar in most respects and they differ in their functional interactions with heterotrimeric G proteins. Both are expressed in neuronal cells. Caveolin-2 was upregulated in response to neuronal cell injury. The CAV2 gene is mapped to 7q31.1-q31.2. The CAV1 gene contains 3 exons, while the human CAV2 gene contains 2 exons. The boundary of the last exon of both are analogous, suggesting that they arose through gene duplication. The genes encoding murine caveolin-1 and -2 are colocalized within the A2 region of mouse chromosome 6.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
P51636
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Amino acids 1-17 (MGLETEKADVQLFMDDD-human) were used as the immunogen for this Caveolin-2 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the Caveolin-2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This Caveolin-2 antibody is available for research use only.
Storage Conditions
After reconstitution, the Caveolin-2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting points. Titration of the Caveolin-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic, nuclear
Image Legend
Western blot testing of Caveolin-2 antibody and Lane 1: rat heart; 2: rat lung; 3: HeLa; 4: A431 cell lysate. Predicted molecular weight ~18 kDa.

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