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ADAMTS4 Antibody

CAT: 0800-R30551Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30551Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
'A disintegrin and metalloproteinase with thrombospondin motifs 4' is an enzyme that in humans is encoded by the ADAMTS4 gene. It is a member of the large ADAMTS family of zinc-dependent proteases. The human ADAMTS4 gene is mapped to chromosome 1 by somatic cell hybrid analysis. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
O75173
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the C-terminus of human ADAMTS4 (RRAQILEILRRRPWAGRK) was used as the immunogen for this ADAMTS4 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the ADAMTS4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This ADAMTS4 antibody is available for research use only.
Storage Conditions
After reconstitution, the ADAMTS4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the ADAMTS4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of ADAMTS4 antibody and Lane 1: rat brain; 2: mouse brain tissue lysate
Product Datasheet
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