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FGFR1 Antibody

CAT: 0800-R30549Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30549Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FGFR1, Fibroblast growth factor receptor 1, also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2/Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. The FGFR1 gene is localized to 8p12-p11.2 by in situ hybridization. FGFR1 is essential for the normal formation of the organ of Corti and that phenotype severity observed in FGFR1 mutants is dependent on the dose of FGFR1. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, squamous cell lung cancer and autosomal dominant Kallmann syndrome 2.
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
P11362
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
An amino acid sequence from the C-terminus of human FGFR1 (CLPRHPAQLANCGLKRR) was used as the immunogen for this FGFR1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the FGFR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This FGFR1 antibody is available for research use only.
Storage Conditions
After reconstitution, the FGFR1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the FGFR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of FGFR1 antibody and Lane 1: rat liver; 2: rat brain; 3: SMMC-7721; 4: HT1080; 5: MM231 cell lysate. Predicted molecular weight: 75-160 kDa depending on glycosylation level.

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