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TIMP1 Antibody

CAT: 0800-R30456Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30456Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tissue inhibitor of metalloproteinases 1 is a glycoprotein that is expressed from the several tissues of organisms. This protein is a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. TIMP1 was found to be located about 22 cM proximal to OTC (300461) .
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL
UniProt
P01033
Host
Rabbit
Reactivity
Human
Immunogen
An amino acid sequence from the C-terminus of human TIMP1 (CLPREPGLCTWQSLRSQIA) was used as the immunogen for this TIMP1 antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, IHC-P
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
Reconstitution
After reconstitution, the TIMP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This TIMP1 antibody is available for research use only.
Storage Conditions
After reconstitution, the TIMP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting amounts. Titration of the TIMP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic, secreted
Image Legend
Western blot testing of TIMP1 antibody and Lane 1: recombinant human protein 10ng; 2: 5ng; 3. 2.5ng

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