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FRZB Antibody

CAT: 0800-R30163Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30163Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FRZB is also known as FRE or OS1. The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility. FRZB is a Wnt-binding protein especially important in embryonic development. It is a competitor for the cell-surface G-protein receptor Frizzled. FRZB is localized in the extracellular plasma membrane. Unlike frizzled, frzb lacks the 7 transmembrane domains normally found in G-protein-coupled receptors. It is still considered a homolog of frizzled because it contains a Cysteine Rich Domain (CRD), and because of its intracellular C-terminus which is crucial for signaling.
CAS Number
9007-83-4
Host
Rabbit
Immunogen
Human partial recombinant protein (AA 176-325) was used as the immunogen for this FRZB antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Format
Antigen affinity purified
Buffer
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Reconstitution
After reconstitution, the FRZB antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This FRZB antibody is available for research use only.

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