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EPO Antibody

CAT: 0800-R30106Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0800-R30106Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EPO, Erythropoietin, is an acidic glycoprotein hormone with a molecular mass of 34 kD. It is a cytokine for erythrocyte (red blood cell) precursors in the bone marrow. This gene is mapped to 7q22.1. It is produced by interstitial fibroblasts in the kidney in close association with peritubular capillary and tubular epithelial cells. It is also produced in perisinusoidal cells in the liver. While liver production predominates in the fetal and perinatal period, renal production is predominant during adulthood. As the prime regulator of red cell production, its major functions are to promote erythroid differentiation and to initiate hemoglobin synthesis. It also has other known biological functions. For example, erythropoietin plays an important role in the brains response to neuronal injury. EPO is also involved in the wound healing process.
CAS Number
9007-83-4
Specifications
Western blot (recombinant protein) : 0.5-1 µg/mL, IHC (FFPE) : 0.5-1 µg/mL, ELISA: 0.1-0.5 µg/mL (human protein tested)
UniProt
P01588
Host
Rabbit
Reactivity
Human
Immunogen
Human partial recombinant protein (AA 1-166) was used as the immunogen for this EPO antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB (recombinant protein), IHC-P, ELISA (recombinant protein)
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 0.025% sodium azide
Reconstitution
After reconstitution, the EPO antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Limitations
This EPO antibody is available for research use only.
Storage Conditions
After reconstitution, the EPO antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
The stated application concentrations are suggested starting points. Titration of the EPO antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of EPO antibody and Lane 1: Recombinant human protein 10ng; 2: 5ng; 3: 2.5ng. Predicted molecular weight: 18-34 kDa depending on glycosylation level.

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