ICAD Antibody
CAT:
800-N1102-25UG
Size:
25 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ICAD Antibody
- Description: During apoptosis, toxic or useless cells are broken down for removal. DFF, or DNA fragmentation factor, is a heterodimeric protein which mediates DNA fragmentation and chromatin condensation during apoptosis. DFFB is the active DFF subunit but remains inactive while bound to DFFA, also call ICAD (Inhibitor of caspase-activated DNase). Caspase-3 cleaves ICAD, which then disassociates from DFFB. The disassociation removes the inhibitory effects of ICAD, activating DFFB and beginning the DNA fragmentation process.
- CAS Number: 9007-83-4
- Host: Rabbit
- Immunogen: A recombinant protein fragment from human ICAD was used as the immunogen for this antibody.
- Clonality: Polyclonal
- Isotype: IgG
- Applications: WB
- Format: Purified
- Buffer: 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
- Reconstitution: Aliquot the antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
- Limitations: This ICAD antibody is available for research use only.