TIMP1 Antibody

• Description :

  TIMP1 belongs to the TIMP family. The proteins in this family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function.

• Specifications :

  Immunofluorescence: 1:10-1:50, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:10-1:50, Western blot: 1:500-1:1000

• UniProt :

  P01033

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  A portion of amino acids 41-70 from the human protein was used as the immunogen for the TIMP1 antibody.

• Clonality :

  Polyclonal

• Isotype :

  Ig

• Applications :

  IF, FACS, IHC-P, WB

• Purity :

  Purified

• Format :

  Purified

• Buffer :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution :

  Aliquot the TIMP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations :

  This TIMP1 antibody is available for research use only.

• Storage Conditions :

  Aliquot the TIMP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes :

  The stated application concentrations are suggested starting points. Titration of the TIMP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number :

  9007-83-4

• Image Legend :

  Western blot testing of human CCRF-CEM cell lysate with TIMP1 antibody. Predicted molecular weight ~23 kDa.