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TIMP1 Antibody

CAT: 0800-F54876-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F54876-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TIMP1 belongs to the TIMP family. The proteins in this family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function.
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:10-1:50, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:10-1:50, Western blot: 1:500-1:1000
UniProt
P01033
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 41-70 from the human protein was used as the immunogen for the TIMP1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IF, FACS, IHC-P, WB
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TIMP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TIMP1 antibody is available for research use only.
Storage Conditions
Aliquot the TIMP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the TIMP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of human CCRF-CEM cell lysate with TIMP1 antibody. Predicted molecular weight ~23 kDa.

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