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Caveolin-3 Antibody / CAV3

CAT: 0800-F54853-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F54853-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CAV3 is a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in its gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD) .
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:1000, Immunohistochemistry (FFPE) : 1:10-1:50, Flow cytometry: 1:10-1:50 (1x10e6 cells)
UniProt
P56539
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 5-31 from the human protein was used as the immunogen for the Caveolin-3 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P, FACS
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Caveolin-3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Caveolin-3 antibody is available for research use only.
Storage Conditions
Aliquot the Caveolin-3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the Caveolin-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
Western blot testing of human HEK293 cell lysate with Caveolin-3 antibody. Predicted molecular weight: ~17 kDa but routinely observed at 20~25 kDa.

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