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HBS1L Antibody

CAT: 0800-F54726-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F54726-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:1000
UniProt
Q9Y450
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 460-486 from the human protein was used as the immunogen for the HBS1L antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the HBS1L antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This HBS1L antibody is available for research use only.
Storage Conditions
Aliquot the HBS1L antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the HBS1L antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of human Jurkat cell lysate with HBS1L antibody. Predicted molecular weight ~75 kDa.

UniProtKB · Q9Y450

HBS1-like protein

HBS1L_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y450
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HBS1L
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.5.-
Processing
—
Secondary accessions
B7Z365, Q4VX89, Q4VX90, Q5T7G3, Q8NDW9, Q9UPW3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasm

Molecular function

Elongation factorHydrolase

Ligand

GTP-bindingNucleotide-binding

Biological process

Protein biosynthesisTranslation regulation

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