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SCNN1A Antibody

CAT: 0800-F54464-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
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CAT#:0800-F54464-0.4MLSize:0.4 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been sociated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids.
CAS Number
9007-83-4
Specifications
Flow cytometry: 1:25 (1x10e6 cells), Immunofluorescence: 1:25, Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000
UniProt
P37088
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 365-391 from the human protein was used as the immunogen for the SCNN1A antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
FACS, IF, IHC-P, WB
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the SCNN1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SCNN1A antibody is available for research use only.
Storage Conditions
Aliquot the SCNN1A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the SCNN1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic, plasma membrane
Image Legend
IHC testing of FFPE human lung carcinoma tissue with SCNN1A antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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