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PIGR Antibody

CAT: 0800-F54456-0.4MLSize: 0.4 mLDry Ice: NoHazardous: No
CAT#: F54456-0.4MLSize: 0.4 mL
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PIGR binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
CAS Number
9007-83-4
Specifications
Flow cytometry: 1:25 (1x10e6 cells), Immunofluorescence: 1:25, Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000
UniProt
P01833
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 646-672 from the human protein was used as the immunogen for the PIGR antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
FACS, IF, IHC-P, WB
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PIGR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PIGR antibody is available for research use only.
Storage Conditions
Aliquot the PIGR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the PIGR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
IHC testing of FFPE human colon tissue with PIGR antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

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