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IFNGR2 Antibody

CAT: 0800-F54438-0.08MLSize: 0.08 mLDry Ice: NoHazardous: No
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CAT#:0800-F54438-0.08MLSize:0.08 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IFNGR2 is the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection.
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:25
UniProt
P38484
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 308-337 from the human protein was used as the immunogen for the IFNGR2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, IHC-P
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the IFNGR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IFNGR2 antibody is available for research use only.
Storage Conditions
Aliquot the IFNGR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
The stated application concentrations are suggested starting points. Titration of the IFNGR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic
Image Legend
Western blot testing of human skeletal muscle lysate with IFNGR2 antibody. Expected molecular weight: 37-55 kDa.

UniProtKB · P38484

Interferon gamma receptor 2

INGR2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P38484
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IFNGR2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IFN-gamma receptor 2, IFN-gamma-R2
EC number
—
Processing
Precursor
Secondary accessions
Q9BTL5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneCytoplasmCytoplasmic vesicleEndoplasmic reticulumGolgi apparatusMembrane

Disease

Disease variant

PTM

Disulfide bondGlycoprotein

Molecular function

Receptor

Domain

RepeatSignalTransmembraneTransmembrane helix

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