PREX1 Antibody

• Description :

  The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs) . It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.

• Specifications :

  Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells)

• UniProt :

  Q8TCU6

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  A portion of amino acids 1134-1163 from the human protein was used as the immunogen for the PREX1 antibody.

• Clonality :

  Polyclonal

• Isotype :

  Ig

• Applications :

  IHC-P, WB, FACS

• Purity :

  Antigen affinity purified

• Format :

  Purified

• Buffer :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution :

  Aliquot the PREX1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations :

  This PREX1 antibody is available for research use only.

• Storage Conditions :

  Aliquot the PREX1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation :

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes :

  The stated application concentrations are suggested starting points. Titration of the PREX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number :

  9007-83-4

• Image Legend :

  IHC testing of FFPE human brain tissue with PREX1 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.