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Lamin B1 Antibody

CAT: 0800-F54037-0.1MLSize: 0.1 mLDry Ice: NoHazardous: No
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CAT#:0800-F54037-0.1MLSize:0.1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
CAS Number
9007-83-4
Specifications
Western blot: 1:500, Immunocytochemistry/Immunofluorescence: 1:100
UniProt
P20700
Host
Mouse
Reactivity
Human, Mouse
Immunogen
A human recombinant protein was used as the immunogen for this Lamin B1 antibody.
Clonality
Monoclonal
Isotype
IgG2b
Clone
5G8-D3-H7
Applications
WB, ICC/IF
Purity
Protein G affinity
Format
Purified
Buffer
Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Reconstitution
Store the Lamin B1 antibody at -20oC.
Limitations
This Lamin B1 antibody is available for research use only.
Storage Conditions
Store the Lamin B1 antibody at -20°C.
Formulation
In PBS with 50% glycerol and 0.03% ProClin 300
Applications Notes
The stated application concentrations are suggested starting points. Titration of the Lamin B1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
ICC/IF staining of HeLa cells, fixed with 4% Paraformaldehyde, using Lamin B1 antibody at 1:100.

UniProtKB · P20700

Lamin-B1

LMNB1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P20700
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LMNB1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2R6J6, Q3SYN7, Q96EI6
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinIsopeptide bondLipoproteinMethylationPhosphoproteinPrenylationUbl conjugation

Coding sequence diversity

Chromosomal rearrangement

Domain

Coiled coil

Disease

Disease variantIntellectual disabilityLeukodystrophyPrimary microcephaly

Cellular component

Intermediate filamentNucleus

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