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FNDC5 Antibody

CAT: 0800-F53982-0.05MLSize: 0.05 mLDry Ice: NoHazardous: No
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CAT#:0800-F53982-0.05MLSize:0.05 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Irisin, also called Fibronectin type III domain-containing protein 5, is a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms.
CAS Number
9007-83-4
Specifications
Western blot: 1:1000-2000
UniProt
Q8NAU1
Host
Mouse
Reactivity
Human
Immunogen
A partial recombinant protein corresponding to amino acids 12-152 from the human protein was used as the immunogen for the FNDC5 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
1736CT532.85.53.92
Applications
WB
Purity
Protein G affinity chromatography
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Irisin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This FNDC5 antibody is available for research use only.
Storage Conditions
Aliquot the FNDC5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the FNDC5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot testing of human skeletal muscle lysate with FNDC5 antibody at 1:2000. Predicted molecular weight: 23 kDa.

UniProtKB · Q8NAU1

Fibronectin type III domain-containing protein 5

FNDC5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8NAU1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FNDC5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A0AA34QVI5, A6NMC9, D3DPQ6, Q6P6D9, Q7Z676
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative promoter usageAlternative splicing

Cellular component

Cell membraneMembranePeroxisomeSecreted

PTM

Glycoprotein

Molecular function

Hormone

Domain

TransmembraneTransmembrane helix

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