RNPS1 Antibody / LDC2

CAT: 0800-F53915-0.2MLSize: 0.2 mLDry Ice: NoHazardous: No
CAT#:0800-F53915-0.2MLSize:0.2 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RNA-binding protein with serine-rich domain 1 is part of pre- and post-splicing multiprotein mRNP complexes. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP and PSAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. The ASAP complex can inhibit RNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis.
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:1000
UniProt
Q15287
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 11-44 from the human protein was used as the immunogen for the RNPS1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the RNPS1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This RNPS1 antibody is available for research use only.
Storage Conditions
Aliquot the RNPS1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the RNPS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine, Mouse, Rat
Image Legend
Western blot testing of human 1) A431, 2) HeLa, 3) HepG2, 4) Jurkat and 5) U-2OS cell lysate with RNPS1 antibody at 1:1000. Predicted molecular weight: 34 kDa.

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