ACE Antibody

CAT: 0800-F53690-0.1MLSize: 0.1 mLDry Ice: NoHazardous: No
CAT#:0800-F53690-0.1MLSize:0.1 mL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:16000
UniProt
P12821
Host
Mouse
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 1274-1306 from the human protein was used as the immunogen for this ACE antibody.
Clonality
Monoclonal
Isotype
IgG2a
Clone
536CT24.1.3
Applications
WB, ELISA
Purity
Ascites
Format
Ascites
Buffer
In ascites with 0.09% sodium azide
Reconstitution
Aliquot the ACE antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ACE antibody is available for research use only.
Storage Conditions
Aliquot the ACE antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In ascites with 0.09% sodium azide
Applications Notes
Titration of the ACE antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
ACE antibody western blot analysis in mouse kidney tissue lysate. Expected molecular weight 140-170 kDa.
Product Datasheet
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