CD40 Antibody

• Description:

  CD40 is the receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. [UniProt]

• Specifications:

  Western blot: 1:100-1:1600

• UniProt:

  P25942

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 247-276 from the human protein was used as the immunogen for this CD40 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Clone:

  647CT13.2.4

• Applications:

  WB, ELISA

• Purity:

  Ascites

• Format:

  Ascites

• Buffer:

  In ascites with 0.09% sodium azide

• Reconstitution:

  Aliquot the CD40 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This CD40 antibody is available for research use only.

• Storage Conditions:

  Aliquot the CD40 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In ascites with 0.09% sodium azide

• Applications Notes:

  Titration of the CD40 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• Prediction Reactivity:

  Mouse, Pig

• CAS Number:

  9007-83-4

• Location:

  Cytoplasmic, cell membrane

• Image Legend:

  CD40 antibody western blot analysis in HL-60 lysate. Predicted molecular weight is 30-45 kDa depending on glycosylation level