CD30 Antibody

• Description:

  The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

• Specifications:

  Western blot: 1:100-1:1000

• UniProt:

  P28908

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 294-321 from the human protein was used as the immunogen for this CD30 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Clone:

  595CT15.5.1

• Applications:

  WB, ELISA

• Purity:

  Ascites

• Format:

  Ascites

• Buffer:

  In ascites with 0.09% sodium azide

• Reconstitution:

  Aliquot the CD30 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This CD30 antibody is available for research use only.

• Storage Conditions:

  Aliquot the CD30 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In ascites with 0.09% sodium azide

• Applications Notes:

  Titration of the CD30 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  CD30 antibody western blot analysis in K562 lysate. Predicted molecular weight: 53-120 kDa depending on glycosylation level.