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CD1a Antibody

CAT: 0800-F53637-0.1MLSize: 0.1 mLDry Ice: NoHazardous: No
CAT#:0800-F53637-0.1MLSize:0.1 mL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:8000
UniProt
P06126
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 76-104 from the human protein was used as the immunogen for this CD1a antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
437CT28.2.1
Applications
WB, ELISA
Purity
Ascites
Format
Ascites
Buffer
In ascites with 0.09% sodium azide
Reconstitution
Aliquot the CD1a antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD1a antibody is available for research use only.
Storage Conditions
Aliquot the CD1a antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In ascites with 0.09% sodium azide
Applications Notes
Titration of the CD1a antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
CD1a antibody western blot analysis in Jurkat lysate. Predicted molecular weight: 37~49 kDa.

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