CD1a Antibody

• Description:

  This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.

• Specifications:

  Western blot: 1:500-1:8000

• UniProt:

  P06126

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A portion of amino acids 76-104 from the human protein was used as the immunogen for this CD1a antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Clone:

  437CT28.2.1

• Applications:

  WB, ELISA

• Purity:

  Ascites

• Format:

  Ascites

• Buffer:

  In ascites with 0.09% sodium azide

• Reconstitution:

  Aliquot the CD1a antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This CD1a antibody is available for research use only.

• Storage Conditions:

  Aliquot the CD1a antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In ascites with 0.09% sodium azide

• Applications Notes:

  Titration of the CD1a antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  CD1a antibody western blot analysis in Jurkat lysate. Predicted molecular weight: 37~49 kDa.