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HIF1A Antibody

CAT: 0800-F53560-0.1MLSize: 0.1 mLDry Ice: NoHazardous: No
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CAT#:0800-F53560-0.1MLSize:0.1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT) . This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.
CAS Number
9007-83-4
Specifications
Western blot: 1:100-1:1000
UniProt
Q16665
Host
Mouse
Reactivity
Human
Immunogen
This HIF1A antibody was produced from mouse immunized with HIF1A recombinant protein.
Clonality
Monoclonal
Isotype
IgM k
Clone
288CT11.7.1
Applications
WB, ELISA
Purity
Ascites
Format
Ascites
Buffer
In ascites with 0.09% sodium azide
Reconstitution
Aliquot the HIF1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This HIF1A antibody is available for research use only.
Storage Conditions
Aliquot the HIF1A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In ascites with 0.09% sodium azide
Applications Notes
Titration of the HIF1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Nuclear, possible cytoplasmic
Image Legend
HIF1A antibody western blot analysis in U251 lysate. Routinely observed molecular weight: 100~120 kDa.
Product Datasheet
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