Caspase-4 Antibody (large subunit)

• Description:

  Involved in the activation cascade of caspases responsible for apoptosis execution. Involved in ER-stress induced apoptosis. Cleaves caspase-1.

• Specifications:

  Western blot: 1:2000

• UniProt:

  P49662

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This Caspase-4 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 163-197 amino acids from the central region of human CASP4.

• Clonality:

  Polyclonal

• Isotype:

  Ig

• Applications:

  WB, ELISA

• Purity:

  Antigen affinity

• Format:

  Antigen affinity purified

• Buffer:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Reconstitution:

  Aliquot the Caspase-4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This Caspase-4 antibody is available for research use only.

• Storage Conditions:

  Aliquot the Caspase-4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  In 1X PBS, pH 7.4, with 0.09% sodium azide

• Applications Notes:

  Titration of the Caspase-4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

• CAS Number:

  9007-83-4

• Image Legend:

  Western blot testing of Caspase-4 antibody at 1:2000 dilution + human Raji lysate; Expected molecular weight ~43 kDa (precursor), ~30 kDa (pro + large subunit), ~20 kDa (large subunit) .